About
T-cell related lymphocyte deficiencies are conditions in which the body’s immune system is not working properly. A person’s immune system is made up of different parts that work together to protect the body from infection. Babies with T-cell deficiencies are born without enough working T-cells, a specific type of white blood cell of the immune system that helps to protect the body from certain kinds of illnesses. From birth, babies with T-cell related lymphocyte deficiencies may not be protected from life-threatening infections. Signs of T-cell related lymphocyte deficiencies include infections that do not get better with antibiotic treatment for two or more months, diarrhea, poor weight gain or growth, and thrush (a fungal infection) in the mouth or throat that does not go away. Early detection through newborn screening and proper treatment can help prevent these infections.
Condition Type:
Frequency:
T-cell related lymphocyte deficiencies are rare. The exact number of babies affected by this condition is unknown.
More Information for Parents:
Also known as:
- T-cell lymphopenia
Core Conditions
- Propionic Acidemia (PROP)
- Methylmalonic Acidemia (Methylmalonyl-CoA Mutase Deficiency) (MUT)
- Methylmalonic Acidemia (Cobalamin Conditions)
- Isovaleric Acidemia (IVA)
- 3-Methylcrotonyl-CoA Carboxylase Deficiency (3-MCC)
- 3-Hydroxy-3-Methylglutaric Aciduria (HMG)
- Holocarboxylase Synthetase Deficiency (MCD)
- Beta-Ketothiolase Deficiency (BKT)
- Glutaric Acidemia, Type I (GA-1)
- Mucopolysaccharidosis, Type II (MPS II)
- Biotinidase Deficiency (BIOT)
- Critical Congenital Heart Disease (CCHD)
- Cystic Fibrosis (CF)
- Classic Galactosemia (GALT)
- Hearing Loss or Varying Hearing Levels
- Severe Combined Immunodeficiency (SCID)
- X-Linked Adrenoleukodystrophy (X-ALD)
- Pompe
- Spinal Muscular Atrophy (SMA)
- Mucopolysaccharidosis, Type I (MPS I)
Secondary
- Citrullinemia, Type II (CIT II)
- Hypermethioninemia (MET)
- Benign Hyperphenylalaninemia (H-PHE)
- Biopterin Defect in Cofactor Biosynthesis (BIOPT-BS)
- Biopterin Defect in Cofactor Regeneration (BIOPT-REG)
- Ornithine Transcarbamylase Deficiency (OTC)
- Carbamoyl Phosphate Synthetase Deficiency (CPS)
- Tyrosinemia, Type II (TYR II)
- Tyrosinemia, Type III (TYR III)